1-Bromo-2-methylpropane → 3-[4-[[3-[Isobutyl(phenyl)amino]benzyl]oxy]phenyl]propanoic acid

HRID 2422314

Reaction equation

HRID 2422314 reaction equation
[NH:1]([C:8]1[CH:9]=[C:10]([CH:25]=[CH:26][CH:27]=1)[CH2:11][O:12][C:13]1[CH:18]=[CH:17][C:16]([CH2:19][CH2:20][C:21]([O:23]C)=[O:22])=[CH:15][CH:14]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:28](Br)[CH:29]([CH3:31])[CH3:30]>>[CH2:28]([N:1]([C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1)[C:8]1[CH:9]=[C:10]([CH:25]=[CH:26][CH:27]=1)[CH2:11][O:12][C:13]1[CH:14]=[CH:15][C:16]([CH2:19][CH2:20][C:21]([OH:23])=[O:22])=[CH:17][CH:18]=1)[CH:29]([CH3:31])[CH3:30]

Participants

3

Reactant 2

HCID 65551-Bromo-2-methylpropaneHCID 57541953Methyl 3-[4-[(3-anilinobenzyl)oxy]phenyl]propanoate

Product 1

HCID 575418363-[4-[[3-[Isobutyl(phenyl)amino]benzyl]oxy]phenyl]propanoic acid

Procedure

The title compound was synthesized in the same manner as in Example 302 from methyl 3-[4-[(3-anilinobenzyl)oxy]phenyl]propanoate and isobutyl bromide. beige powder (yield 12%). MS (APCI−): 402 (M−H).

Sources & evidence

ORD record
ord-edae8e1da7384e6cb9008e73850166e5
Source dataset
uspto-grants-2011_06
Patent number
US07960369B2

Linked notes

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