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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2422607Generated: October 24, 2026

Methylamine → 8-chloro-2-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-3-methylquinazolin-4(3H)-one

https://huagongshe.com/en/reaction/2422607

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethylamineHCID 6329—
Reactant2-Amino-3-chlorobenzoic acidHCID 80807—
Reactant4-[(1-Cyclobutyl-4-piperidinyl)oxy]benzaldehydeHCID 86624461—
Product8-chloro-2-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-3-methylquinazolin-4(3H)-oneHCID 11618702—

Reaction Steps

The entitled compound was obtained according to the method of Example 15 but starting from 2-amino-3-chlorobenzoic acid, methylamine and 4-[(1-cyclobutyl-4-piperidinyl)oxy]benzaldehyde.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07960394B2
Source datasetuspto-grants-2011_06
ORD IDord-272eec8d53bc46e8b0dbd0bcf10fbd54
Source noteuspto-grants-2011_06