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Thionyl Chloride → 3-Chloro-5-(chloromethyl)pyridine hydrochloride

HRID 2424893
Notes
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Reaction equation

HRID 2424893 reaction equation
O[CH2:2][C:3]1[CH:4]=[C:5]([Cl:9])[CH:6]=[N:7][CH:8]=1.S(Cl)([Cl:12])=O>>[ClH:9].[Cl:9][C:5]1[CH:6]=[N:7][CH:8]=[C:3]([CH2:2][Cl:12])[CH:4]=1
ParticipantsProcedureSources & evidenceReaction notes

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 25067264(5-Chloropyridin-3-yl)methanol

Product 1

HCID 672463053-Chloro-5-(chloromethyl)pyridine hydrochloride

Procedure

The title compound was prepared in accordance with the general method of example E from 5-(hydroxymethyl)-3-chloropyridine and thionylchloride.

Sources & evidence

ORD record
ord-921d50e0343f45ca8a8a9aaabeb8d959
Source dataset
uspto-grants-2011_06
DOI
10.6084/m9.figshare.5104873.v1
Patent number
US07964620B2

Reaction notes

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On this pageParticipantsProcedureSources & evidenceReaction notes