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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2425212Generated: October 24, 2026

4-Fluorohippuric acid → 4-fluoro-N-(2-oxo-2-(phenyl(3-(trifluoromethyl)phenyl)methylamino)ethyl)benzamide

https://huagongshe.com/en/reaction/2425212

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluorohippuric acidHCID 699341—
ReactantPhenyl(3-(trifluoromethyl)phenyl)methanamineHCID 21528802—
Product4-fluoro-N-(2-oxo-2-(phenyl(3-(trifluoromethyl)phenyl)methylamino)ethyl)benzamideHCID 24899995—

Reaction Steps

Prepared in analogy to example 1.1 from (4-fluoro-benzoylamino)-acetic acid (CA [366-79-0]) and rac-C-phenyl-C-(3-trifluoromethyl-phenyl)-methylamine (CA [70428-92-1]). MS (m/e): 429.4 (MH−, 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07964645B2
Source datasetuspto-grants-2011_06
ORD IDord-1c91cc83172042f793d5e1c0d2de7597
Source noteuspto-grants-2011_06