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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2425266Generated: October 24, 2026

Thiophene-3-carboxylic acid → Thiophene-3-carboxylic acid ({[bis-(3-fluoro-phenyl)-methyl]-carbamoyl}-methyl)-amide

https://huagongshe.com/en/reaction/2425266

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThiophene-3-carboxylic acidHCID 6918—
Reactant2-amino-N-[bis-(3-fluoro-phenyl)-methyl]-acetamideHCID 59689153—
ProductThiophene-3-carboxylic acid ({[bis-(3-fluoro-phenyl)-methyl]-carbamoyl}-methyl)-amideHCID 24897004—

Reaction Steps

Prepared in analogy to example 1.12 from 2-amino-N-[bis-(3-fluoro-phenyl)-methyl]-acetamide (example 3.4) and thiophene-3-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07964645B2
Source datasetuspto-grants-2011_06
ORD IDord-4d1934d145294cc78e8a644214c2cdff
Source noteuspto-grants-2011_06