Thionyl Chloride → HCID 59855123, compound

Reaction equation

S(Cl)([Cl:3])=O.[Cl:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]2[CH:17]=[CH:16][CH:15]=[C:14]([CH2:18]O)[CH:13]=2)=[C:8]([CH3:20])[CH:7]=1>>[Cl:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]2[CH:17]=[CH:16][CH:15]=[C:14]([CH2:18][Cl:3])[CH:13]=2)=[C:8]([CH3:20])[CH:7]=1

Participants

Reactant 2

HCID 24386Thionyl Chloride

HCID 598551374′-Chloro-2′-methyl[1,1′-biphenyl]-3-methanol

Product 1

HCID 59855123HCID 59855123, compound

Procedure

Thionyl chloride was added to (4′-chloro-2′-methylbiphenyl-3-yl)methanol under cooing with ice-methanol, followed by stirring at room temperature for 1 hour to obtain 4-chloro-3′-(chloromethyl)-2-methylbiphenyl.

Sources & evidence

ORD record: ord-d81e0433ed444afb83a1ba8f139b6315
Source dataset: uspto-grants-2011_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07968552B2

Reaction notes

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