3-Methoxyaniline → N-(3-Methoxy-phenyl)-2-nitro-benzamide

HRID 2431

Reaction equation

HRID 2431 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([NH2:9])[CH:4]=1.[N+:10]([C:13]1[CH:21]=[CH:20][CH:19]=[CH:18][C:14]=1[C:15](O)=[O:16])([O-:12])=[O:11]>>[N+:10]([C:13]1[CH:21]=[CH:20][CH:19]=[CH:18][C:14]=1[C:15]([NH:9][C:5]1[CH:6]=[CH:7][CH:8]=[C:3]([O:2][CH3:1])[CH:4]=1)=[O:16])([O-:12])=[O:11]

Participants

3

Reactant 2

HCID 108243-MethoxyanilineHCID 110872-Nitrobenzoic acid

Product 1

HCID 542853N-(3-Methoxy-phenyl)-2-nitro-benzamideYield 85%

Procedure

Using m-anisidine (2.03 g, 16.5 mmol) and 2-nitrobenzoic acid (2.51 g, 15.0 mmol), the procedure of Reference Example 16 was repeated to obtain 3.47 g (84.9%) of the title compound in the form of light yellow needle crystals.

Sources & evidence

ORD record
ord-dfd5a32f672c46c19f0d787eab887512
Source dataset
uspto-grants-1998_03
Patent number
US05728835

Linked notes

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