5-fluoro-1,3-dihydro-2H-indol-2-one → HCID 54324035, compound

HRID 24400

Reaction equation

HRID 24400 reaction equation
[CH:1]([C:4]1[CH:5]=[C:6]([CH:9]=[CH:10][C:11]=1[O:12][CH3:13])[CH:7]=O)([CH3:3])[CH3:2].[F:14][C:15]1[CH:16]=[C:17]2[C:21](=[CH:22][CH:23]=1)[NH:20][C:19](=[O:24])[CH2:18]2>>[F:14][C:15]1[CH:16]=[C:17]2[C:21](=[CH:22][CH:23]=1)[NH:20][C:19](=[O:24])[C:18]2=[CH:7][C:6]1[CH:9]=[CH:10][C:11]([O:12][CH3:13])=[C:4]([CH:1]([CH3:3])[CH3:2])[CH:5]=1

Participants

3

Reactant 2

HCID 37310125-fluoro-1,3-dihydro-2H-indol-2-oneHCID 98989903-Isopropyl-4-methoxybenzaldehyde

Product 1

HCID 54324035HCID 54324035, compound

Procedure

3-Isopropyl-4-methoxybenzaldehyde was condensed with 5-fluoro-2-oxindole to give 0.25 g of 5-fluoro-3-(3-isopropyl-4-methoxybenzylidene)-1,3-dihydroindol-2-one as a yellow-orange solid.

Sources & evidence

ORD record
ord-f580f628f1274f7a9052b8b32faccc2b
Source dataset
uspto-grants-2005_02
Patent number
US06855730B2

Linked notes

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