Benzylamine → 3-(Benzylamino)-1,1,1-trifluoropropan-2-ol
Reaction equation
[CH2:1]([NH2:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[F:9][C:10]([F:15])([F:14])[CH:11]1[CH2:13][O:12]1>>[CH2:1]([NH:8][CH2:13][CH:11]([OH:12])[C:10]([F:15])([F:14])[F:9])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1Participants
3
Procedure
Starting material: benzylamine and 2-(trifluoromethyl)oxirane
Sources & evidence
- ORD record
- ord-72a0ed4de4964b35bec4b347589b987a
- Source dataset
- uspto-grants-2014_02
- Patent number
- US08658641B2
Reaction notes
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