Hydrazine → HCID 14299774, compound
Reaction equation
[Cl:1][C:2]1([C:7]([O:9]CC)=O)[CH2:4][C:3]1([Cl:6])[Cl:5].[NH2:12][NH2:13]>C(O)C>[Cl:1][C:2]1([C:7]([NH:12][NH2:13])=[O:9])[CH2:4][C:3]1([Cl:6])[Cl:5]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
A solution of ethyl 1,2,2-trichlorocyclopropane carboxylate (3 grams), ethanol (25 ml), and anhydrous hydrazine (0.48 grams) was heated to reflux for approximately 2 hours. The reaction mixture was cooled, the solvent was stripped from solution, and the residue was recrystallized using a small volume of ethanol to produce 1,2,2-trichlorocyclopropane carboxylic acid hydrazide (mp 122°-123° C.). The identity of the final product was confirmed by NMR analysis.
Workup
- temperatureto reflux for approximately 2 hours
- temperatureThe reaction mixture was cooled
- customthe residue was recrystallized
Sources & evidence
- ORD record
- ord-f0762804feaf4586a1d43cccf14ae924
- Source dataset
- uspto-grants-1987_11
- Patent number
- US04704156
Reaction notes
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