Chlorine → 1-Chloro-4-(trifluoromethoxy)benzene

HRID 246898

Reaction equation

HRID 246898 reaction equation
[Cl:1]Cl.[N+]([C:6]1[CH:11]=[CH:10][C:9]([O:12][C:13]([F:16])([F:15])[F:14])=[CH:8][CH:7]=1)([O-])=O>>[Cl:1][C:6]1[CH:11]=[CH:10][C:9]([O:12][C:13]([F:16])([F:15])[F:14])=[CH:8][CH:7]=1

Participants

3

Reactant 2

HCID 24526Chlorine2×HCID 5224051-Nitro-4-(trifluoromethoxy)benzene

Product 1

HCID 27772731-Chloro-4-(trifluoromethoxy)benzeneYield 83%

Procedure

Chlorine and p-nitrotrifluoromethoxybenzene (10.7 parts) were fed simultaneously at a molar ratio of 3:1, Cl2 : organic reactant, into a vapor phase reactor maintained at 300° to 320° C. over a 30 minute period to yield 8.2 parts of p-chlorotrifluoromethoxybenzene (83% yield). The structure of the product was confirmed by gas chromatographic-mass spectrum and F19 nuclear magnetic resonance analysis.

Workup

  1. temperatureorganic reactant, into a vapor phase reactor maintained at 300° to 320° C. over a 30 minute period

Sources & evidence

ORD record
ord-4cbebf0936474408b6dc36d8d22c9472
Source dataset
uspto-grants-1987_11
Patent number
US04704483

Linked notes

Loading…