Dimethylamine → 2-[2-(Dimethylamino)ethyl]-2,3-dihydro-4,7-dimethyl-1,4-oxazepino[6,7-h]quinoline-5(4H)-thione hydrochloride
Reaction equation
[Cl:1][CH2:2][CH2:3][CH:4]1[CH2:19][N:18]([CH3:20])[C:17](=[S:21])[C:7]2[CH:8]=[C:9]([CH3:16])[C:10]3[CH:11]=[CH:12][CH:13]=[N:14][C:15]=3[C:6]=2[O:5]1.[CH3:22][NH:23][CH3:24]>>[ClH:1].[CH3:22][N:23]([CH3:24])[CH2:2][CH2:3][CH:4]1[CH2:19][N:18]([CH3:20])[C:17](=[S:21])[C:7]2[CH:8]=[C:9]([CH3:16])[C:10]3[CH:11]=[CH:12][CH:13]=[N:14][C:15]=3[C:6]=2[O:5]1Participants
3
Procedure
Following the procedure of Example 31, 2-(2-chloroethyl)-2,3-dihydro-4,7-dimethyl-1,4-oxazepino[6,7-h]quinoline-5(4H)-thione is reacted with dimethylamine to give the title compound.
Sources & evidence
- ORD record
- ord-5fd50b7c2dfc4a158a98568f1845a0a6
- Source dataset
- uspto-grants-1987_11
- Patent number
- US04705853