Isopropylamine → HCID 20160907, compound
Reaction equation
[CH2:1]([C:3]([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)([CH2:6][CH:7]1[CH2:9][O:8]1)[C:4]#[N:5])[CH3:2].[CH:16]([NH2:19])([CH3:18])[CH3:17]>C(O)C>[CH2:1]([C:3]1([C:10]2[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=2)[C:4](=[NH:5])[O:8][CH:7]([CH2:9][NH:19][CH:16]([CH3:18])[CH3:17])[CH2:6]1)[CH3:2]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
A solution of α-ethyl-α-phenyloxiranepropanenitrile and isopropylamine in ethanol is placed in a pressure bottle and heated overnight in a steam bath. After cooling, the bottle is opened and the solvent removed in vacuo. Solvent-solvent extraction by the method described in Example 4 yields the title compound.
Workup
- temperatureheated overnight in a steam bath
- temperatureAfter cooling
- customthe solvent removed in vacuo
- extractionSolvent-solvent extraction by the method
Sources & evidence
- ORD record
- ord-6a56ac0048ea420d99a51e6f874802a7
- Source dataset
- uspto-grants-1987_11
- Patent number
- US04707499
Reaction notes
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