Sodium Hydroxide → 4-[[(Z)-(2-oxo-1H-indol-3-ylidene)-phenylmethyl]amino]benzoic acid

HRID 24747

Reaction equation

HRID 24747 reaction equation
C([O:3][C:4]([C:6]1[CH:11]=[CH:10][C:9]([NH:12]/[C:13](=[C:20]2\[C:21](=[O:29])[NH:22][C:23]3[C:28]\2=[CH:27][CH:26]=[CH:25][CH:24]=3)/[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[CH:8][CH:7]=1)=[O:5])C.[OH-].[Na+]>C(O)C>[C:4]([C:6]1[CH:7]=[CH:8][C:9]([NH:12]/[C:13](=[C:20]2\[C:21](=[O:29])[NH:22][C:23]3[C:28]\2=[CH:27][CH:26]=[CH:25][CH:24]=3)/[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[CH:10][CH:11]=1)([OH:5])=[O:3]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 178469015HCID 178469015, compound

Product 1

HCID 1785170884-[[(Z)-(2-oxo-1H-indol-3-ylidene)-phenylmethyl]amino]benzoic acid

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Prepared analogously to Example 8 from (Z)-3-[1-(4-ethoxycarbonyl-phenylamino]-1-phenyl-methylidene]-2-indolinone and sodium hydroxide solution in ethanol.

Sources & evidence

ORD record
ord-c74e5d1bd3d1410aad5b7c2a1b5f362a
Source dataset
uspto-grants-2005_02
Patent number
US06855710B2

Linked notes

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