Lithium → 1-(1-benzylpyrrolidin-3-yl)-N-methylmethanamine

HRID 247850

Reaction equation

HRID 247850 reaction equation
[CH3:1][NH:2][C:3]([CH:5]1[CH2:9][N:8]([CH2:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[C:7](=O)[CH2:6]1)=O.[Li].[H-].[Al+3].[H-].[H-]>>[CH2:10]([N:8]1[CH2:7][CH2:6][CH:5]([CH2:3][NH:2][CH3:1])[CH2:9]1)[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Participants

4

Reactant 3

HCID 3028194LithiumHCID 134917941-benzyl-N-methyl-5-oxopyrrolidine-3-carboxamideHCID 21584524Aluminiumhydride

Product 1

HCID 46608321-(1-benzylpyrrolidin-3-yl)-N-methylmethanamine

Procedure

40 g of the compound obtained in stage A is reduced by means of 13.1 g of lithium and aluminum hydride.

Sources & evidence

ORD record
ord-ef6bfa4b7f8343b2a9ad6c070a815f75
Source dataset
uspto-grants-1993_05
Patent number
US05208243

Linked notes

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