3,5-Dibromo-4-Hydroxybenzaldehyde → 5-[(3,5-Dibromo-4-hydroxyphenyl)methylene]-1-methyl-2,4-imidazolidinedione

HRID 247884

Reaction equation

[Br:1][C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([Br:11])[C:9]=1[OH:10])[CH:5]=O.[CH3:12][N:13]1[CH2:19][C:17](=[O:18])[NH:16][C:14]1=[O:15]>>[Br:1][C:2]1[CH:3]=[C:4]([CH:5]=[C:19]2[N:13]([CH3:12])[C:14](=[O:15])[NH:16][C:17]2=[O:18])[CH:7]=[C:8]([Br:11])[C:9]=1[OH:10]

Participants

Reactant 2

HCID 181003,5-Dibromo-4-Hydroxybenzaldehyde

HCID 692171-Methylhydantoin

Product 1

HCID 539952775-[(3,5-Dibromo-4-hydroxyphenyl)methylene]-1-methyl-2,4-imidazolidinedioneYield 72.7%

Procedure

Prepared according to the procedure described in Example 99 using 3,5-dibromo-4-hydroxybenzaldehyde (8.4 g, 30 mmoles) and 1-methyl hydantoin (3.5 g, 30 mmoles) to afford the pure product (8.2 g), mp 271°-277° C.

Workup

customPrepared

Sources & evidence

ORD record: ord-069e4f49a0594774bd14630391a42a19
Source dataset: uspto-grants-1993_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05208250

Linked notes

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