HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → 1-Acetyl-3-{1-ethoxy-1-phenylmethylidene}-5-nitro-2-indolinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Benzene, (triethoxymethyl)- | HCID 74268 | — |
| Reactant | 5-Nitro-2-oxindole | HCID 230366 | — |
| Product | 1-Acetyl-3-{1-ethoxy-1-phenylmethylidene}-5-nitro-2-indolinone | HCID 54280104 | — |
Reaction Steps
5.07 g (23 mmol) of 5-nitro-2-indolinone are stirred for 2.5 hours at 100° C. together with 15.5 g (69 mmol) of triethyl orthobenzoate in 50 ml of acetic anhydride. After cooling, 100 ml of ether/petroleum ether (1:1) are added. The precipitate formed is suction filtered, washed with ether/petroleum ether (1:1) and dried.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06855710B2 |
| Source dataset | uspto-grants-2005_02 |
| ORD ID | ord-f80aa130a7ce4fa2a1c476d0dbda6d50 |
| Source note | uspto-grants-2005_02 |