1,2,3-Trichlorobenzene → 2,3-Dichlorobenzenethiol
Reaction equation
[Cl:1][C:2]1[C:3]([Cl:9])=[C:4](Cl)[CH:5]=[CH:6][CH:7]=1.[SH-:10].[Na+]>N.C([O-])(=O)C.[Cu+2].C([O-])(=O)C>[Cl:1][C:2]1[C:3]([Cl:9])=[C:4]([SH:10])[CH:5]=[CH:6][CH:7]=1Participants
5
Reactant 2
Product 1
Reagents, catalysts & solvents 2
Procedure
The method in which trichlorobenzene and sodium hydrosulfide are reacted at 125° C. under increased pressure in liquid ammonia solvent in the presence of copper acetate catalyst for 10 hours to yield dichlorothiophenol, which is then reacted with sodium monochloroacetate to yield dichlorophenylthioglycolic acid with a yield of 14 to 29% [Kogyo Kagaku Zasshi, 70, 1384 (1967)].
Sources & evidence
- ORD record
- ord-2bd4c8012f3f46bbb1e19f148e73c859
- Source dataset
- uspto-grants-1993_05
- Patent number
- US05210291
Reaction notes
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