N-methyl-4-nitrophenethylamine → 4-[2-(Methylamino)ethyl]aniline

HRID 24921

Reaction equation

HRID 24921 reaction equation

[CH3:1][NH:2][CH2:3][CH2:4][C:5]1[CH:10]=[CH:9][C:8]([N+:11]([O-])=O)=[CH:7][CH:6]=1>CO.[Pd]>[CH3:1][NH:2][CH2:3][CH2:4][C:5]1[CH:6]=[CH:7][C:8]([NH2:11])=[CH:9][CH:10]=1

Participants

4

Reactant 1

HCID 2794239N-methyl-4-nitrophenethylamine

Product 1

HCID 102409734-[2-(Methylamino)ethyl]aniline

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalyst

HCID 887MethanolSolvent

Procedure

Prepared by catalytic hydrogenation of 4-(2-methylamino-ethyl)-nitrobenzene over palladium-charcoal in methanol analogously to Example 39c.

Sources & evidence

ORD record: ord-b2f48efb89f346118109ec56490efcc6
Source dataset: uspto-grants-2005_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06855710B2

Linked notes

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