4-(Azetidin-1-yl-methyl)-nitrobenzene → 4-[(Azetidin-1-yl)methyl]aniline

HRID 24929

Reaction equation

HRID 24929 reaction equation
[N:1]1([CH2:5][C:6]2[CH:11]=[CH:10][C:9]([N+:12]([O-])=O)=[CH:8][CH:7]=2)[CH2:4][CH2:3][CH2:2]1>[Ni]>[N:1]1([CH2:5][C:6]2[CH:11]=[CH:10][C:9]([NH2:12])=[CH:8][CH:7]=2)[CH2:2][CH2:3][CH2:4]1

Participants

3

Reactant 1

HCID 225696534-(Azetidin-1-yl-methyl)-nitrobenzene

Product 1

HCID 225694404-[(Azetidin-1-yl)methyl]aniline

Reagents, catalysts & solvents 1

HCID 935NickelCatalyst

Procedure

Prepared analogously to Example 55 by catalytic hydrogenation of 4-(azetidin-1-yl-methyl)-nitrobenzene with Raney nickel as a light brown oil.

Sources & evidence

ORD record
ord-5bf4125367024ff59c7f4229429ce03d
Source dataset
uspto-grants-2005_02
Patent number
US06855710B2

Linked notes

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