Pyridine, 2,6-dichloro-3-(chloromethyl)- → 1-(2,6-Dimethylpyridin-4-yl)-N-methylmethanamine

HRID 249490

Reaction equation

HRID 249490 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([CH2:8]Cl)[CH:5]=[C:4]([CH3:10])[N:3]=1.Cl[C:12]1C(CCl)=CC=C(Cl)[N:13]=1>>[CH3:1][C:2]1[CH:7]=[C:6]([CH2:8][NH:13][CH3:12])[CH:5]=[C:4]([CH3:10])[N:3]=1

Participants

3

Reactant 2

HCID 6451791Pyridine, 2,6-dichloro-3-(chloromethyl)-HCID 135828144-(Chloromethyl)-2,6-dimethylpyridine

Product 1

HCID 224503691-(2,6-Dimethylpyridin-4-yl)-N-methylmethanamine

Procedure

The reaction according to Reference Example 11 was carried out using (2,6-dimethyl-4-pyridyl)methyl chloride in lieu of 2,6-dichloro-3-pyridylmethyl chloride to give the title compound as oil.

Sources & evidence

ORD record
ord-88792ddd6f2042c59952e55fe1388d0f
Source dataset
uspto-grants-1993_05
Patent number
US05214152

Linked notes

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