Pyridine, 2,6-dichloro-3-(chloromethyl)- → 2-Chloro-3-[(methylamino)methyl]pyridine

HRID 249493

Reaction equation

HRID 249493 reaction equation
[Cl:1][C:2]1[C:7]([CH2:8]Cl)=[CH:6][CH:5]=[CH:4][N:3]=1.Cl[C:11]1C(CCl)=CC=C(Cl)[N:12]=1>>[Cl:1][C:2]1[C:7]([CH2:8][NH:12][CH3:11])=[CH:6][CH:5]=[CH:4][N:3]=1

Participants

3

Reactant 2

HCID 6451791Pyridine, 2,6-dichloro-3-(chloromethyl)-HCID 115283992-Chloro-3-chloromethyl-pyridine

Product 1

HCID 224504442-Chloro-3-[(methylamino)methyl]pyridine

Procedure

The reaction according to Reference Example 11 was carried out using (2-chloro-3-pyridyl)methyl chloride in lieu of 2,6-dichloro-3-pyridylmethyl chloride to give the title compound as a yellow oil.

Sources & evidence

ORD record
ord-0640a27714104e6d970478ec1d6032b0
Source dataset
uspto-grants-1993_05
Patent number
US05214152

Linked notes

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