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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 253339Generated: October 25, 2026

3-Methoxybenzaldehyde → 4-Iodomethyl-2-(3-methoxyphenyl)-5-phenyloxazole

https://huagongshe.com/reaction/253339

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-MethoxybenzaldehydeHCID 11569—
Reactant1,2-Propanedione, 1-phenyl-, 2-oximeHCID 6399024—
Reactant4-Iodomethyl-5-phenyl-2-p-tolyloxazoleHCID 57434504—
Product4-Iodomethyl-2-(3-methoxyphenyl)-5-phenyloxazoleHCID 57434505—

Reaction Steps

Analogously to the building block synthesis of 4-iodomethyl-5-phenyl-2-p-tolyloxazole, 1-phenyl-1,2-propanedione-2-oxime and m-anisaldehyde gave 4-iodomethyl-2-(3-methoxyphenyl)-5-phenyloxazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07872034B2
Source datasetuspto-grants-2011_01
ORD IDord-af8bf56934244487be13ba3055663c04
Source noteuspto-grants-2011_01