Reaction equation
[I:1][CH2:2][C:3]1[N:4]=[C:5]([C:14]2C=C[C:17]([CH3:20])=[CH:16][CH:15]=2)[O:6][C:7]=1[C:8]1C=CC=CC=1.C/C(/C(C)=O)=N\[OH:24].CC1OC(C=O)=CC=1>>[I:1][CH2:2][C:3]1[N:4]=[C:5]([C:14]2[O:24][C:17]([CH3:20])=[CH:16][CH:15]=2)[O:6][C:7]=1[CH3:8]Participants
4
Procedure
Analogously to the building block synthesis of 4-iodomethyl-5-phenyl-2-p-tolyloxazole, diacetylmonoxime and 5-methylfuran-2-carbaldehyde gave 4-iodomethyl-5-methyl-2-(5-methylfuran-2-yl)oxazole.
Sources & evidence
- ORD record
- ord-bc85954b03364772a279996244495d58
- Source dataset
- uspto-grants-2011_01
- Patent number
- US07872034B2
Linked notes
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