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Aniline → N-Phenylmaleimide

HRID 25355
Notes
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Reaction equation

HRID 25355 reaction equation
[C:1]1(=[O:7])O[C:4](=[O:5])[CH:3]=[CH:2]1.[NH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>>[C:9]1([N:8]2[C:4](=[O:5])[CH:3]=[CH:2][C:1]2=[O:7])[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1
ParticipantsProcedureSources & evidenceReaction notes

Participants

3

Reactant 2

HCID 6115AnilineHCID 7923Maleic Anhydride

Product 1

HCID 13662N-Phenylmaleimide

Procedure

Aniline, a primary aromatic amine, is a hazardous carcinogenic liquid. It is difficult to handle aniline safely during reactive extrusion, which is the most economical way to produce imides on a large scale. Often maleic anhydride is reacted with aniline to obtain the N-phenylmaleimide monomer, which is then copolymerized with other monomers in solution or emulsion polymerization processes.

Sources & evidence

ORD record
ord-30146fe15b274c13a4d8e818e865f959
Source dataset
uspto-grants-2005_02
DOI
10.6084/m9.figshare.5104873.v1
Patent number
US06858672B2

Reaction notes

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On this pageParticipantsProcedureSources & evidenceReaction notes