3-Chloropropanesulphonyl chloride → HCID 178461041, compound
Reaction equation
[Cl:1][C:2]1[S:6][C:5]([NH:7][C:8](=[O:23])[N:9]([C@H:16]2[CH2:21][CH2:20][C@H:19]([CH3:22])[CH2:18][CH2:17]2)[CH:10]2[CH2:15][CH2:14][NH:13][CH2:12][CH2:11]2)=[N:4][CH:3]=1.Cl[CH2:25][CH2:26][CH2:27][S:28](Cl)(=[O:30])=[O:29]>>[Cl:1][C:2]1[S:6][C:5]([NH:7][C:8](=[O:23])[N:9]([C@H:16]2[CH2:21][CH2:20][C@H:19]([CH3:22])[CH2:18][CH2:17]2)[CH:10]2[CH2:11][CH2:12][N:13]([S:28]([CH2:27][CH2:26][CH3:25])(=[O:30])=[O:29])[CH2:14][CH2:15]2)=[N:4][CH:3]=1Participants
3
Procedure
Prepared as described in general procedure (G) using 3-(5-chloro-thiazol-2-yl)-1-(trans-4-methyl-cyclohexyl)-1-piperidin-4-yl-urea and 3-chloropropane-1-sulfonyl chloride
Workup
- customPrepared
Sources & evidence
- ORD record
- ord-624ab8c2224d4722a42677174f391f99
- Source dataset
- uspto-grants-2011_01