HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → N-(4-Fluoro-2-(4-methyl-1H-imidazol-1-yl)phenyl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 4-Fluoro-2-(4-methyl-1H-imidazol-1-yl)aniline | HCID 57732445 | — |
| Product | N-(4-Fluoro-2-(4-methyl-1H-imidazol-1-yl)phenyl)acetamide | HCID 57732446 | 64% |
Reaction Steps
Reaction of intermediate 2A (17.5 g, 91.4 mmol) and acetic anhydride (90 mL, 914 mmol) provided the product 3A as an off-white powder (13.5 g, 64% yield). EIMS 234.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07875618B2 |
| Source dataset | uspto-grants-2011_01 |
| ORD ID | ord-49d3eb530c804cd2bbf6799cdfdc0461 |
| Source note | uspto-grants-2011_01 |