HCID 178418443, compound → HCID 178448984, compound

HRID 254561Notes

Reaction equation

HRID 254561 reaction equation
[CH2:1](/[N:5]=[CH:6]/[C:7]1[C:12]([F:13])=[CH:11][CH:10]=[C:9]([Cl:14])[C:8]=1Cl)[CH2:2][CH2:3][CH3:4].[CH2:16]([Mg]Br)[CH3:17]>[Cl-].[Mn+2].[Cl-]>[CH2:1](/[N:5]=[CH:6]/[C:7]1[C:12]([F:13])=[CH:11][CH:10]=[C:9]([Cl:14])[C:8]=1[CH2:16][CH3:17])[CH2:2][CH2:3][CH3:4]

Participants

4

Reactant 2

HCID 178418443HCID 178418443, compoundHCID 178448985HCID 178448985, compound

Product 1

HCID 178448984HCID 178448984, compound

Reagents, catalysts & solvents 1

HCID 10313134Manganese(2+) dichlorideCatalyst

Procedure

Butyl-[1-(3-chloro-2-ethyl-6-fluoro-phenyl)-meth-(E)-ylidene]-amine was prepared from butyl-[1-(2,3-dichloro-6-fluoro-phenyl)-meth-(E)-ylidene]-amine, ethylmagnesium bromide and manganese(II) chloride in analogy to Example 194a): yellow oil; 1H-NMR (CDCl3): 0.97 (3H, t, CH3), 1.15 (3H, t, CH3), 1.43 (2H, sextet, CH2), 1.70 (2H, quintet, CH2), 3.06 (2H, q, CH2), 3.66 (2H, t, CH2), 6.88 (1H, dd, ArH), 7.34 (1H, dd, ArH), 8.51 (1H, s, CH═N).

Sources & evidence

ORD record
ord-af4a293d29d641059909e9ed9cf5b8a3
Source dataset
uspto-grants-2011_01
Patent number
US07875645B2

Reaction notes

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