4-Isothiocyanatobenzenesulfonamide → HCID 10204395, compound

HRID 25506

Reaction equation

HRID 25506 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=[C:2]1[C:10]1[CH:11]=[CH:12][C:13]([O:17][CH3:18])=[C:14]([NH2:16])[CH:15]=1.[N:19]([C:22]1[CH:27]=[CH:26][C:25]([S:28]([NH2:31])(=[O:30])=[O:29])=[CH:24][CH:23]=1)=[C:20]=[S:21]>>[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=[C:2]1[C:10]1[CH:11]=[CH:12][C:13]([O:17][CH3:18])=[C:14]([NH:16][C:20](=[S:21])[NH:19][C:22]2[CH:27]=[CH:26][C:25]([S:28]([NH2:31])(=[O:29])=[O:30])=[CH:24][CH:23]=2)[CH:15]=1

Participants

3

Reactant 2

HCID 5213594-IsothiocyanatobenzenesulfonamideHCID 99002045-(1H-indol-2-yl)-2-methoxy-phenylamine2×

Product 1

HCID 10204395HCID 10204395, compound

Procedure

The product from Example 1, Step B, 5-(1H-indol-2-yl)-2-methoxy-phenylamine (0.12 g, 0.1 mmol) was reacted with 4-isothiocyanatobenzene sulfonamide (0.108 g, 0.1 mmol) according to the procedure for Example 2 to give the product (0.14 g).

Sources & evidence

ORD record
ord-0c92b7ab11774c20ab29507f5b0b0831
Source dataset
uspto-grants-2005_02
Patent number
US06858739B2

Linked notes

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