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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 25604Generated: October 26, 2026

Trifluoroacetic acid → HCID 178464455, compound

https://huagongshe.com/reaction/25604

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
Reactant2-(Ethylamino)ethanolHCID 8072—
Reactant4-(Trifluoromethyl)benzenesulfonyl chlorideHCID 2777399—
ReactantHCID 178484796HCID 178484796—
ProductHCID 178464455HCID 178464455—

Reaction Steps

In analogy to examples 29.10 and 29.11, trans-Methansulfonic acid 5-(4-methyl amino-cyclohexyl)-pentyl ester.trifluoroacetic acid salt and 4-(trifluoromethyl)benzenesulphonyl chloride were reacted, followed by treatment with 2-ethylamino-ethanol to yield trans-N-(4-{5-[Ethyl-(2-hydroxy-ethyl)-amino]-pentyl}-cyclohexyl)-N-methyl-4-trifluoromethyl-benzenesulfonamide, MS: 479 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06858651B2
Source datasetuspto-grants-2005_02
ORD IDord-efb5a997550142f4b024f995dd4838b7
Source noteuspto-grants-2005_02