Chlorine → 2,3-Dichloro-5-(trichloromethyl)pyridine

HRID 256212

Reaction equation

[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([Cl:11])([Cl:10])[Cl:9])=[CH:4][N:3]=1.[Cl:12]Cl>>[Cl:1][C:2]1[C:7]([Cl:12])=[CH:6][C:5]([C:8]([Cl:9])([Cl:10])[Cl:11])=[CH:4][N:3]=1

Participants

Reactant 2

HCID 24526Chlorine

HCID 502932-Chloro-5-trichloromethylpyridine

Product 1

HCID 946472,3-Dichloro-5-(trichloromethyl)pyridine

Procedure

Instead of isolating the 2-chloro-5-(trichloromethyl)-pyridine from this mixture, the above-described mixture is reacted with chlorine according to the conditions of the present invention as described herein to form 2,3-dichloro-5-(trichloromethyl)pyridine. The resulting 2,3-dichloro-5-(trichloromethyl)pyridine is separated from the reaction mixture by distillation, crystal refining, recrystallization from a solvent or a combination thereof.

Sources & evidence

ORD record: ord-8b9a8af931f642f395be17353d236fdc
Source dataset: uspto-grants-1987_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04701532

Linked notes

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