HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 1-Amino-1-(2,2,5,5-tetramethyl-1-cyclopentyl)ethenylcyclopropane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | N-Boc-1-amino-1-(2,2,5,5-tetramethyl-1-cyclopentyl)ethenylcyclopropane | HCID 70445455 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | 1-Amino-1-(2,2,5,5-tetramethyl-1-cyclopentyl)ethenylcyclopropane | HCID 20164442 | — |
Reaction Steps
N-Boc-1-amino-1-(2,2,5,5-tetramethyl-1-cyclopentyl)ethenylcyclopropane is dissolved in trifluoroacetic acid and the solution is stirred overnight. Water is added and the mixture is made basic with 20% KOH. The mixture is extracted with ether, and the organic layer is dried over Na2SO4 and is evaporated to yield 1-amino-1-(2,2,5,5-tetramethyl-1-cyclopentyl)ethenylcyclopropane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04701552 |
| Source dataset | uspto-grants-1987_10 |
| ORD ID | ord-16f2d819cebb44f8822ed9377ae0db88 |
| Source note | uspto-grants-1987_10 |