Hydrazine → 2-Hydrazinyl-5-nitropyridine

HRID 257427

Reaction equation

HRID 257427 reaction equation
Cl[C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[CH:4][N:3]=1.[NH2:11][NH2:12]>O1CCOCC1>[NH:11]([C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[CH:4][N:3]=1)[NH2:12]

Participants

4

Reactant 2

HCID 9321HydrazineHCID 783082-Chloro-5-nitropyridine

Product 1

HCID 40319312-Hydrazinyl-5-nitropyridineYield 10.3%

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

2-Chloro-5-nitropyridine (5 g, 31.5 mmol) and hydrazine (1.74 g, 34.7 mmol) were dissolved in 60 ml of dioxane, and the solution was stirred at room temperature for 16 hours. The precipitated yellow powder (m.p.: 198°-208°0 C.) was collected by filtration to obtain 502 mg of the intended product as a hydrochloride salt.

Workup

  1. filtrationThe precipitated yellow powder (m.p.: 198°-208°0 C.) was collected by filtration

Sources & evidence

ORD record
ord-89e96cc5cced4b9a8bfc6c804e32859e
Source dataset
uspto-grants-1993_11
Patent number
US05262415

Linked notes

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