4-Ethylpyridine → 1-(2-Fluorophenyl)-3-(4-pyridyl)-butane

HRID 257458

Reaction equation

HRID 257458 reaction equation
[CH2:1]([C:3]1[CH:8]=[CH:7][N:6]=[CH:5][CH:4]=1)[CH3:2].[F:9][C:10]1[CH:18]=[CH:17][CH:16]=[CH:15][C:11]=1[CH2:12][CH2:13]Br>>[F:9][C:10]1[CH:18]=[CH:17][CH:16]=[CH:15][C:11]=1[CH2:12][CH2:13][CH:1]([C:3]1[CH:8]=[CH:7][N:6]=[CH:5][CH:4]=1)[CH3:2]

Participants

3

Reactant 2

HCID 108224-EthylpyridineHCID 27569642-Fluorophenethyl bromide

Product 1

HCID 197833551-(2-Fluorophenyl)-3-(4-pyridyl)-butaneYield 39.2%

Procedure

1.0 g (9.35 mmol) of 4-ethylpyridine and 1.90 g (9.35 mmol) of 2-fluorophenethyl bromide were reacted in the same manner as in Example 1. The reaction product was purified, to obtain 0.74 g of desired compound (yield: 39.2%).

Workup

  1. customThe reaction product was purified

Sources & evidence

ORD record
ord-fd8adcaacb1a48c6a99eba5034a642b8
Source dataset
uspto-grants-1993_11
Patent number
US05262420

Linked notes

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