4-Ethylpyridine → HCID 19783323, compound

Reaction equation

[CH2:1]([C:3]1[CH:8]=[CH:7][N:6]=[CH:5][CH:4]=1)[CH3:2].[F:9][C:10]([F:21])([F:20])[C:11]1[CH:12]=[C:13]([CH:17]=[CH:18][CH:19]=1)[CH2:14][CH2:15]Br>>[F:9][C:10]([F:21])([F:20])[C:11]1[CH:12]=[C:13]([CH2:14][CH2:15][CH:1]([C:3]2[CH:8]=[CH:7][N:6]=[CH:5][CH:4]=2)[CH3:2])[CH:17]=[CH:18][CH:19]=1

Participants

Reactant 2

HCID 108224-Ethylpyridine

HCID 5945351-(2-Bromoethyl)-3-(trifluoromethyl)benzene

Product 1

HCID 19783323HCID 19783323, compoundYield 15.3%

Procedure

1.0 g (9.35 mmol) of 4-ethylpyridine and 2.37 g (9.35 mmol) of 3-trifluoromethylphenethyl bromide were reacted in the same manner as in Example 1. The reaction product was purified to obtain 0.40 g of the desired compound (yield: 15.3%).

Workup

customThe reaction product was purified

Sources & evidence

ORD record: ord-b4d1128d52804dd5ae28aba2497326e8
Source dataset: uspto-grants-1993_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05262420

Reaction notes

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