3-Ethyl-4-methylpyridine → 1-(2-Chlorophenyl)-3-(3-ethyl-4-pyridyl)-propane

HRID 257471

Reaction equation

HRID 257471 reaction equation
[CH2:1]([C:3]1[CH:4]=[N:5][CH:6]=[CH:7][C:8]=1[CH3:9])[CH3:2].[Cl:10][C:11]1[CH:19]=[CH:18][CH:17]=[CH:16][C:12]=1[CH2:13][CH2:14]Br>>[Cl:10][C:11]1[CH:19]=[CH:18][CH:17]=[CH:16][C:12]=1[CH2:13][CH2:14][CH2:9][C:8]1[CH:7]=[CH:6][N:5]=[CH:4][C:3]=1[CH2:1][CH3:2]

Participants

3

Reactant 2

HCID 682543-Ethyl-4-methylpyridineHCID 27569631-(2-Bromoethyl)-2-chlorobenzene

Product 1

HCID 197833621-(2-Chlorophenyl)-3-(3-ethyl-4-pyridyl)-propaneYield 42.8%

Procedure

1.13 g (9.35 mmol) of 3-ethyl-4-methylpyridine and 2.05 g (9.35 mmol) of 2-chlorophenethyl bromide were reacted in the same manner as in Example 1. The reaction product was purified to obtain 1.04 g of the desired compound (yield: 42.8%).

Workup

  1. customThe reaction product was purified

Sources & evidence

ORD record
ord-4d3b0c970a4d41008320fae4a382b56f
Source dataset
uspto-grants-1993_11
Patent number
US05262420

Linked notes

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