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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 25758Generated: October 27, 2026

2-Furanmethanethiol → [6-(2-Methoxyphenyl)-2,2-dimethyl-1,2-dihydroquinolin-4-ylmethyl]phenylamine

https://huagongshe.com/reaction/25758

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-FuranmethanethiolHCID 7363—
ReactantPotassium CarbonateHCID 11430—
Reactant4-(Furan-3-ylmethylsulfanylmethyl)-6-(2-methoxyphenyl)-2,2-dimethyl-1,2-dihydroquinolineHCID 11741195—
Reactant4-(Bromomethyl)-6-(2-methoxyphenyl)-2,2-dimethyl-1,2-dihydroquinolineHCID 22566535—
Product[6-(2-Methoxyphenyl)-2,2-dimethyl-1,2-dihydroquinolin-4-ylmethyl]phenylamineHCID 10406857—

Reaction Steps

4-(Furan-3-ylmethylsulfanylmethyl)-6-(2-methoxyphenyl)-2,2-dimethyl-1,2-dihydroquinoline 80 mg of 4-bromomethyl-6-(2-methoxyphenyl)-2,2-dimethyl-1,2-dihydroquinoline, 69 mg of potassium carbonate, and 45 μL of furfuryl mercaptan reacted to give 9 mg of the title compound as a foam.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06858627B2
Source datasetuspto-grants-2005_02
ORD IDord-021f85b5aeea43379c33c8ff003f81a4
Source noteuspto-grants-2005_02