Benzenepropanoic acid, 4-hydroxy-, methyl ester → Methyl 3-[4-[(4,5-diphenyl-2-oxazolyl)methoxy]phenyl]propanoate

HRID 257630

Reaction equation

HRID 257630 reaction equation
Br[CH2:2][C:3]1[O:4][C:5]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[N:7]=1.[OH:20][C:21]1[CH:26]=[CH:25][C:24]([CH2:27][CH2:28][C:29]([O:31][CH3:32])=[O:30])=[CH:23][CH:22]=1>>[C:8]1([C:6]2[N:7]=[C:3]([CH2:2][O:20][C:21]3[CH:22]=[CH:23][C:24]([CH2:27][CH2:28][C:29]([O:31][CH3:32])=[O:30])=[CH:25][CH:26]=3)[O:4][C:5]=2[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1

Participants

3

Reactant 2

HCID 79706Benzenepropanoic acid, 4-hydroxy-, methyl esterHCID 5685992-Bromomethyl-4,5-diphenyl-oxazole

Product 1

HCID 19783602Methyl 3-[4-[(4,5-diphenyl-2-oxazolyl)methoxy]phenyl]propanoate

Procedure

Reaction of 2-bromomethyl-4,5-diphenyloxazole and methyl 3-(4-hydroxyphenyl)propanoate according to the procedure of Example 17 provided the title compound, m.p. 92°-95° C.

Sources & evidence

ORD record
ord-d911e77471b34ff5bbbf1692cfb05d57
Source dataset
uspto-grants-1993_11
Patent number
US05262540

Linked notes

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