Ethylenediamine → beta-(4-Acetamidophenoxyacetamido)ethylamine

HRID 258753

Reaction equation

[C:1]([NH:4][C:5]1[CH:17]=[CH:16][C:8]([O:9][CH2:10][C:11]([O:13]CC)=O)=[CH:7][CH:6]=1)(=[O:3])[CH3:2].[CH2:18]([NH2:21])[CH2:19][NH2:20]>>[C:1]([NH:4][C:5]1[CH:6]=[CH:7][C:8]([O:9][CH2:10][C:11]([NH:20][CH2:19][CH2:18][NH2:21])=[O:13])=[CH:16][CH:17]=1)(=[O:3])[CH3:2]

Participants

Reactant 2

HCID 3301Ethylenediamine

HCID 309738Ethyl 2-(4-acetamidophenoxy)acetate

Product 1

HCID 53735279beta-(4-Acetamidophenoxyacetamido)ethylamine

Procedure

In a similar manner using 23.7 g. of ethyl 4-acetamidophenoxyacetate and 60 ml. of ethylenediamine as starting materials there is obtained β-(4-acetamidophenoxyacetamido)ethylamine, m.p. 210°-212° C.

Sources & evidence

ORD record: ord-d6d7044bdc364f9e9b30a56585c5c28b
Source dataset: uspto-grants-1977_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04034106

Linked notes

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