N-bromobutanimide → 3,6-Dibromoisobenzofuran-1(3H)-one
Reaction equation
[Br:1][C:2]1[CH:11]=[C:10]2[C:5]([CH2:6][O:7][C:8]2=[O:9])=[CH:4][CH:3]=1.[Br:12]N1C(=O)CCC1=O.N(CCCC#N)=NCCCC#N>C(Cl)(Cl)(Cl)Cl>[Br:12][CH:6]1[C:5]2[C:10](=[CH:11][C:2]([Br:1])=[CH:3][CH:4]=2)[C:8](=[O:9])[O:7]1Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
6-Bromophthalide (5.85 gms; 0.0275 mole), N-bromosuccinimide (4.89 gm; 0.0275 mole) and azobisbutyronitrile (0.1 gm) were gently refluxed in dry carbon tetrachloride (200 ml.) for 2 hours. On cooling, the succinimide was filtered off and the solvent removed in vacuo to give an oil, which was used immediately.
Workup
- temperatureOn cooling
- filtrationthe succinimide was filtered off
- customthe solvent removed in vacuo
- customto give an oil, which
Sources & evidence
- ORD record
- ord-23a4df72807d4b6487d6dc5c09f1fc0c
- Source dataset
- uspto-grants-1977_07
- Patent number
- US04036829
Reaction notes
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