Formaldehyde → peri-Naphthalide

Reaction equation

C=O.[OH-].[K+].[CH:5]1[CH:10]=[C:9]([CH:11]=O)[C:8]2[C:13]([C:17]([OH:19])=[O:18])=[CH:14][CH:15]=[CH:16][C:7]=2[CH:6]=1>>[CH2:11]1[O:19][C:17](=[O:18])[C:13]2=[CH:14][CH:15]=[CH:16][C:7]3=[C:8]2[C:9]1=[CH:10][CH:5]=[CH:6]3

Participants

Reactant 3

HCID 712Formaldehyde

HCID 14797Potassium Hydroxide

HCID 798818-Formyl-1-naphthalenecarboxylic acid

Product 1

HCID 223824peri-Naphthalide

Procedure

Prepared by the action of formalin and potassium hydroxide on peri-naphthaldehydic acid by the method of Fuson et. al. (J. Amer. Chem. Soc. 71, 1870).

Sources & evidence

ORD record: ord-02fd48eab69f4ce5857b10d1f462ef0b
Source dataset: uspto-grants-1977_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04036829

Reaction notes

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