Benzene → Isobutylidenebenzhydrylamine
Reaction equation
[CH:1](=O)[CH:2]([CH3:4])[CH3:3].[CH:6]([NH2:19])([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1.C1C=CC=CC=1>O>[CH:1](=[N:19][CH:6]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[CH:2]([CH3:4])[CH3:3]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
14.4 parts of isobutyraldehyde was added to 36.6 parts of benzhydrylamine in 100 parts of dry benzene at room temperature with stirring. The cloudy mixture was heated to reflux with water-separation for 4 hours. On cooling the solution was filtered to remove a small amount of solid and evaporated to give isobutylidenebenzhydrylamine.
Workup
- temperatureThe cloudy mixture was heated
- temperatureOn cooling the solution
- filtrationwas filtered
- customto remove a small amount of solid
- customevaporated
Sources & evidence
- ORD record
- ord-c6b653a08d6e4a9db8afca08018af3b1
- Source dataset
- uspto-grants-1979_04
- Patent number
- US04147780
Reaction notes
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