Benzene → Isobutylidenebenzhydrylamine

HRID 25972

Reaction equation

HRID 25972 reaction equation
[CH:1](=O)[CH:2]([CH3:4])[CH3:3].[CH:6]([NH2:19])([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1.C1C=CC=CC=1>O>[CH:1](=[N:19][CH:6]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[CH:2]([CH3:4])[CH3:3]

Participants

5

Reactant 3

HCID 241BenzeneHCID 6561IsobutyraldehydeHCID 7036Benzhydrylamine

Product 1

HCID 10657527Isobutylidenebenzhydrylamine

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

14.4 parts of isobutyraldehyde was added to 36.6 parts of benzhydrylamine in 100 parts of dry benzene at room temperature with stirring. The cloudy mixture was heated to reflux with water-separation for 4 hours. On cooling the solution was filtered to remove a small amount of solid and evaporated to give isobutylidenebenzhydrylamine.

Workup

  1. temperatureThe cloudy mixture was heated
  2. temperatureOn cooling the solution
  3. filtrationwas filtered
  4. customto remove a small amount of solid
  5. customevaporated

Sources & evidence

ORD record
ord-c6b653a08d6e4a9db8afca08018af3b1
Source dataset
uspto-grants-1979_04
Patent number
US04147780

Linked notes

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