(+-)-Methyl mandelate → Methyl phenylglyoxalate

HRID 259895

Reaction equation

HRID 259895 reaction equation
[C:1]([O:11][CH3:12])(=[O:10])[CH:2]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)[OH:3]>CO>[C:4]1([C:2](=[O:3])[C:1]([O:11][CH3:12])=[O:10])[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1

Participants

3

Reactant 1

HCID 78066(+-)-Methyl mandelate2×

Product 1

HCID 84835Methyl phenylglyoxalate

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The procedures of Example 1 were repeated except for employing the above-obtained catalyst (8 ml), feeding air and nitrogen at feed rates of 35 ml/min. and 70 ml/min., respectively, and feeding a methyl mandelate solution comprising methanol and methyl mandelate (6:1, by weight) at a feed rate of 17.0 g/hr., to carry out the gaseous catalytic reaction. There was obtained methyl phenylglyoxylate as α-keto acid ester. The results are set forth in Table 5.

Workup

  1. customthe gaseous catalytic reaction

Sources & evidence

ORD record
ord-16f44b1b14b84e858f643fd6690b3e3a
Source dataset
uspto-grants-1996_06
Patent number
US05523459

Linked notes

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