Ethanol → Etilevodopa
Reaction equation
[O:1]=[C:2]([C@H:4]([CH2:6][C:7]1[CH:14]=[C:12]([OH:13])[C:10]([OH:11])=[CH:9][CH:8]=1)[NH2:5])[OH:3].S(Cl)(Cl)=O.[CH2:19](O)[CH3:20]>>[CH3:19][CH2:20][O:1][C:2]([C@@H:4]([NH2:5])[CH2:6][C:7]1[CH:8]=[CH:9][C:10]([OH:11])=[C:12]([OH:13])[CH:14]=1)=[O:3]Participants
4
Procedure
reacting L-DOPA with ethanol in the presence of thionyl chloride or an acid catalyst to yield crude L-DOPA ethyl ester,
Sources & evidence
- ORD record
- ord-2866e6b8a0674158b0c117e79a86fb7d
- Source dataset
- uspto-grants-1996_06
- Patent number
- US05525631
Reaction notes
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