1-Bromo-2-Chloroethane → N-[2-[4-[(1-methylethyl)thio]phenoxy]ethyl]octylamine hydrochloride
Reaction equation
[Cl:1][CH2:2][CH2:3][O:4][C:5]1[CH:10]=[CH:9]C(SC)=C[CH:6]=1.C[S:14][C:15]1[CH:20]=CC(O)=C[CH:16]=1.Cl[CH2:23][CH2:24]Br.[CH2:26]([NH2:34])[CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH3:33]>>[ClH:1].[CH3:16][CH:15]([S:14][C:24]1[CH:23]=[CH:6][C:5]([O:4][CH2:3][CH2:2][NH:34][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH3:33])=[CH:10][CH:9]=1)[CH3:20]Participants
5
Procedure
According to the procedure of Example 1, 1-chloro-2-[4-(methylthio)phenoxy]ethane from 4-(methylthio)phenol and 1-chloro-2-bromoethane is reacted with n-octylamine to provide N-[2-[4-[(1-methylethyl)thio]phenoxy]ethyl]octylamine hydrochloride.