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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 260488Generated: October 27, 2026

1-Methylhistamine → 3-(benzenesulfonyl)-5-chloro-N-[2-(1-methylimidazol-4-yl)ethyl]-1H-indole-2-carboxamide

https://huagongshe.com/reaction/260488

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-MethylhistamineHCID 3614—
Reactant3-Phenylsulfonyl-5-chloroindole-2-carboxylic acidHCID 15813516—
Product3-(benzenesulfonyl)-5-chloro-N-[2-(1-methylimidazol-4-yl)ethyl]-1H-indole-2-carboxamideHCID 483545—

Reaction Steps

Reaction of 3-phenylsulfonyl-5-chloroindole-2-carboxylic acid with 1-methylhistamine under the conditions of Example 37 provides the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05527819
Source datasetuspto-grants-1996_06
ORD IDord-f30d33a02a124acc91a98c094c48e24d
Source noteuspto-grants-1996_06