2-Bromobutane → 3-Methyl-2-(2-naphthyl)butyronitrile

HRID 261142Notes

Reaction equation

HRID 261142 reaction equation
C(Br)(CC)C.[CH:6]([CH:10]([C:13]1[CH:22]=[CH:21][C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH:14]=1)[C:11]#[N:12])([CH2:8]C)[CH3:7]>>[CH:6]([CH:10]([C:13]1[CH:22]=[CH:21][C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH:14]=1)[C:11]#[N:12])([CH3:8])[CH3:7]

Participants

3

Reactant 2

HCID 65542-BromobutaneHCID 20395159alpha-Sec-butyl-2-naphthaleneacetonitrile

Product 1

HCID 223937393-Methyl-2-(2-naphthyl)butyronitrile

Procedure

This procedure is repeated in all essential details excepting that isobutyl bromide (1-bromo-2-methylpropane) is substituted for 2-bromopropane. This latter procedure yields α-isobutyl-2-naphthaleneacetonitrile. When the procedure is repeated with sec-butylbromide the corresponding α-sec-butyl-2-naphthaleneacetonitrile is obtained.

Workup

  1. customis obtained

Sources & evidence

ORD record
ord-0de1fe726b9b42168b11a17783e0f6d3
Source dataset
uspto-grants-1979_08
Patent number
US04164415

Reaction notes

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