Phenol, 2,6-bis(1,1-dimethylethyl)-4-nitroso- → 4-Amino-2,6-di-tert-butylphenol

HRID 261741

Reaction equation

HRID 261741 reaction equation
[C:1]([C:5]1[CH:10]=[C:9]([N:11]=O)[CH:8]=[C:7]([C:13]([CH3:16])([CH3:15])[CH3:14])[C:6]=1[OH:17])([CH3:4])([CH3:3])[CH3:2].[H][H]>[Pd].C(O)C>[C:1]([C:5]1[CH:10]=[C:9]([NH2:11])[CH:8]=[C:7]([C:13]([CH3:16])([CH3:15])[CH3:14])[C:6]=1[OH:17])([CH3:4])([CH3:3])[CH3:2]

Participants

5

Reactant 2

HCID 70383Phenol, 2,6-bis(1,1-dimethylethyl)-4-nitroso-HCID 178418361HCID 178418361, compound

Product 1

HCID 3142204-Amino-2,6-di-tert-butylphenol

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

2,6-di tert.butyl-4-aminophenol was prepared by hydrogenating a mixture of 23.5 grams of 2,6-di tert.butyl-4-nitrosophenol, 2 grams of 5% Palladium on carbon, and 200 milliliters of absolute ethanol in a Parr Pressure Reaction Apparatus. The reduction was accomplished in 1 hour at a maximum hydrogen pressure of 50 psi and a maximum temperature of 50° C. The resulting solution of 2,6-di tert.butyl-4-aminophenol was removed from the Pressure Apparatus and filtered to remove the catalyst.

Workup

  1. customin a Parr Pressure Reaction Apparatus
  2. customa maximum temperature of 50° C
  3. customThe resulting solution of 2,6-di tert.butyl-4-aminophenol was removed from the Pressure Apparatus
  4. filtrationfiltered
  5. customto remove the catalyst

Sources & evidence

ORD record
ord-02082f82b5dc4dbcbea7f30a89d500c5
Source dataset
uspto-grants-1979_05
Patent number
US04152319

Linked notes

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