Acetic-formic anhydride → 2-Bromo-4-formamido-5-methylthiazole

HRID 26203

Reaction equation

HRID 26203 reaction equation
[NH2:1][C:2]1[N:3]=[C:4]([Br:8])[S:5][C:6]=1[CH3:7].[C:9](OC=O)(=[O:11])C>>[Br:8][C:4]1[S:5][C:6]([CH3:7])=[C:2]([NH:1][CH:9]=[O:11])[N:3]=1

Participants

3

Reactant 2

HCID 75269Acetic-formic anhydrideHCID 202940282-Bromo-5-methylthiazol-4-amine

Product 1

HCID 203771742-Bromo-4-formamido-5-methylthiazole

Procedure

4-Amino-2-bromo-5-methylthiazole is treated with formic-acetic anhydride (prepared as described in Example 12b) to give the title compound.

Sources & evidence

ORD record
ord-3c524703835241c88e7052e046c91c1d
Source dataset
uspto-grants-1979_04
Patent number
US04148904

Linked notes

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