Amphetamine → Ammonia

HRID 26266

Reaction equation

HRID 26266 reaction equation
[CH3:1][CH:2]([NH2:10])[CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[Li]>>[NH3:10].[NH2:10][CH:2]([CH3:1])[CH2:3][C:4]1[CH2:9][CH:8]=[CH:7][CH2:6][CH:5]=1

Participants

4

Reactant 2

HCID 3007AmphetamineHCID 3028194Lithium

Product 2

HCID 222AmmoniaHCID 213253691-(2-Aminopropyl)-1,4-cyclohexadiene

Procedure

12 g. (0.09 moles) of α-methylphenethylamine is reduced by treatment with 4 g. of lithium in 0.5 l. of ammonia according to procedure of Example 1(a) to yield 1-(2-aminopropyl)-1,4-cyclohexadiene.

Sources & evidence

ORD record
ord-1569ca0dbbdc4c24bdc2910ed33a91da
Source dataset
uspto-grants-1979_04
Patent number
US04149001

Linked notes

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